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Sat Jul 4

• Dopamine D1 and D5 Receptors Are Localized to Discrete Populations of Interneurons in Primate Prefrontal Cortex -- Glausier et al. 19 (8): 1820 -- Cerebral Cortex: D1 was the predominant D1R subtype in PV interneurons and was found mainly in dendrites. In contrast, D5 was the predominant D1R subtype in CR interneurons and was found mainly in dendrites.

Thu Jul 2

• Ligand-Gated Chloride Channels Are Receptors for Biogenic Amines in C. elegans -- Ringstad et al. 325 (5936): 96 -- Science: LGC-53 is a high-affinity dopamine receptor, LGC-55 is a high-affinity tyramine receptor, and LGC-40 is a low-affinity serotonin receptor that is also gated by choline and acetylcholine. All are ligand-gated chloride channels.
• DECONSTRUCTING THE VANILLA MILKSHAKE: THE DOMINANT EFFECT OF SUCROSE ON SELF-ADMINISTR ATION OF NUTRIENT-FLAVO R MIXTURES

Wed Jul 1

• Dopamine Transporters in Striatum may contribute to modulation of Attention
• New, Unmedicated Parkies Have Trouble Learning From Rewards: So, if you have early Parkinson?s disease, you?re not taking meds for it yet, and your wife says you?ll get some extra lovin? if you do the dishes tonight? a newly-released test reveals the new Parkie might not LEARN that ?taking out garbage? equals ?extra lovin??.

Mon Jun 29

• Mind Hacks: The straight dopamine theory could be up in smoke
• Ventral Tegmental Area BDNF Induces an Opiate-Depende nt-Like Reward State in Naive Rats -- Vargas-Perez et al. 324 (5935): 1732 -- Science: A single infusion of BDNF into the VTA promotes a shift from a dopamine-indep endent to a dopamine-depen dent opiate reward system, identical to that seen when an opiate-naïve rat becomes dependent and withdrawn. This shift involves a switch in the {gamma}-aminob utyric acid type A (GABAA) receptors of VTA GABAergic neurons, from inhibitory to excitatory signaling.
• Dopaminergic transplantatio n for parkinson's disease: Current status and future prospects: "Collecti vely, these findings do not bode well for the short-term future of cell-based dopaminergic therapies in Parkinson' ;s disease."

Sat Jun 27

• Low Dopamine Levels ==> How to Increase?: Got the remainder of my most recent blood test results. Dopamine level is really, really low. I don't have the paperwork in front of me, but my

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